Effects of MK801 on evoked potentials, spinal cord blood flow and cord edema in acute spinal cord injury in rats
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چکیده
منابع مشابه
Spinal cord blood flow and systemic blood pressure after experimental spinal cord injury in rats.
We looked at the relation between systemic arterial blood pressure and recovery from spinal cord injury by inducing both hypertension and hypotension in 25 rats randomly allocated to five equal groups. The rats received no injury, a mild (2.3-g), or a severe (53.0-g) spinal cord injury lasting 1 minute. We used the hydrogen clearance technique to measure spinal cord blood flow at the injury sit...
متن کاملFailure of topical DMSO to improve blood flow or evoked potentials in rat spinal cord injury.
Dimethyl sulfoxide (DMSO) is a well-known hydroxyl radical scavenger, which is readily absorbed through biological membranes. We studied the effects of locally applied DMSO on acute spinal cord injury. Either 10% DMSO in saline (n=8) or saline alone (n=7) was applied directly to the exposed cervical spinal cord of rats 1 hour after clip compression injury of 26 g force for 1 minute. The outcome...
متن کاملEFFECTS OF CIS APRIDE ON CONS TIPATION DUE TO SPINAL CORD INJURY: REPORT OF FIVE WARFARE SPINAL CORD INJURED PATIENTS
Five warfare spinal cord injured patients with intractable constipation are described. Treatment with cisapride (4 x 10 mg daily) was undertaken. The agent cisapride significantly reduced the oral-anal transit time from 25.2 days to 14.4 days. It also improved other subjective complaints of these patients markedly. No side effects were seen during the trial.
متن کاملNatural Polyphenols and Spinal Cord Injury
Polyphenols have been shown to have some of the neuroprotective effects against neurodegenerative diseases. These effects are attributed to a variety of biological activities, including free radical scavenging/antioxidant and anti-inflammatory and anti-apoptotic activities. In this regard, many efforts have been made to study the effects of various well-known dietary polyphenols on spinal cord ...
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ژورنال
عنوان ژورنال: Spinal Cord
سال: 1999
ISSN: 1362-4393,1476-5624
DOI: 10.1038/sj.sc.3100941